Abstract

RODRIGUEZ ARIAS, Edwin Andrés et al. Rapidly evolving cryoglobulinemic vasculitis. Rev. argent. reumatolg. [online]. 2023, vol.34, n.3, pp.94-98. ISSN 0327-4411.  http://dx.doi.org/10.47196/rar.v34i3.777.

Vasculitis is manifested by inflammation of the blood vessels, affecting from the capillaries to the largest vessels. Dermatological compromise due to vasculitis ranges from mild cases that generate superficial involvement to ulcers and necrosis of different tissues. Cryoglobulinemia is characterized by the presence of serum cryoglobulins, which precipitate at temperatures below 37 degrees Celsius. It is associated with infectious, immune-mediated, and lymphoproliferative diseases, especially infection by the hepatitis C virus. Vasculitis in the context of cryoglobulins is produced by immune complex deposits in capillaries, arterioles, and small and medium-sized arteries. Treatment is based on treating the underlying cause and modulating the inflammatory response.

We present the case of a 50-year-old man, with a history of chronic hepatitis B, who presented acute and critical ischemia of both extremities, documenting cryoglobulinemic vasculitis with poor evolution.

Keywords : vasculitis; cryoglobulinemia.

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