Abstract

AVENA, Sergio A. et al. Gene mixture in a population sample from Buenos Aires City. Medicina (B. Aires) [online]. 2006, vol.66, n.2, pp.113-118. ISSN 0025-7680.

The aim of this study is to estimate the gene admixture in the population of Buenos Aires City from samples of blood donors, which come from a public health centre (Hospital de Clínicas). These studies were performed on 218 unrelated people,  who donated  blood during the year 2002. Eight erythrocyte genetic systems and GM/KM allotypes were analysed. A survey to obtain information about place of birth, present residence and genealogical data of the donors was performed. The gene frequencies were determined using  a  method of  maximum likelihood. The genetic admixture was calculated through the ADMIX program (trihibride). The Amerindian and African contributions were 15.8% and 4.3% respectively. These data were compared with those obtained in a previous study performed in a private centre (Hospital Italiano de Buenos Aires) and significant differences were observed, except in the KM system. The results obtained are in concordance with the demographic and historic information of  Buenos Aires City.

Keywords : gene mixture; genetic markers; migrations; public and private hospital.

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