Abstract

PENSA, Lucila A. et al. Pulmonary alveolar proteinosis. Medicina (B. Aires) [online]. 2021, vol.81, n.2, pp.301-303. ISSN 0025-7680.

Pulmonary alveolar proteinosis (PAP) is a rare, diffuse pulmonary disease due to abnormal surfactant homeostasis. We present the case of a 69-year-old woman who was admitted to the hospital for progressive dyspnea with marked limitation in activity, and non-productive cough, of three months of evolution. Type I respiratory failure was confirmed. Chest tomography findings were interlobular and intralobular septal thickening, ground glass opacities and bilateral consolidation. Histological diagnosis was made and whole-lung lavage was performed with clinical improvement. We highlight the need to keep in mind differential diagnoses of respiratory failure and pulmonary infiltrates during COVID-19 pandemic, even rare entities such as PAP.

Keywords : Pulmonary alveolar proteinosis; Surfactant; Macrophage; Pulmonary lavage.

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