Abstract

DI PRINZIO, Anamá; TORRE, Ana C.; PEREZ RIOS, Susana E.  and  MAZZUOCCOLO, Luis D.. Bazex syndrome: a rare paraneoplastic disease. Medicina (B. Aires) [online]. 2024, vol.84, n.1, pp.163-167. ISSN 0025-7680.

Bazex syndrome is a paraneoplastic disorder most commonly linked to squamous cell carcinomas of the upper aerodigestive tract, followed by lung cancer and other malignancies. It manifests through three stages of skin involvement that mirror the tumor’s progression. Remarkably, skin lesions precede tumor symptoms or diagnosis in two-thirds of cases, underscoring the cru cial role of suspecting this condition as it can promptly reveal an underlying neoplasm. Treatment primarily focuses on addressing the root neoplasm, with recurrent skin lesions potentially indicating tumor relapse.

In this context, we present a clinical case involving a male patient whose manifestation of this syndrome facilitated the timely diagnosis of lung adenocarcinoma. This case underscores the significance of understand ing this uncommon syndrome and its link to cancer, enabling early and accurate oncological diagnosis.

Keywords : Bazex syndrome; Paraneoplastic syn drome; Lung cancer; Psoriasiform dermatitis.

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