Abstract

BUERO, Agustín et al. Malignant melanotic nerve sheath tumor of the posterior mediastinum. Medicina (B. Aires) [online]. 2024, vol.84, n.2, pp.324-. ISSN 0025-7680.

Melanotic schwannoma (MS) is a rare and infrequent subtype of schwannoma characterized by cytoplasmic deposits of melanosomes (melanin). Unlike the other schwannomas, it could have malignant transforma tion. Due to distinctive characteristics and atypical behavior from classic schwannomas subtypes, MS were renamed and reclassified as “melanocytic malignant neural sheath tumor” in the 5th ed. of the World Health Organization’s classification of central nervous system tumors in 2021. We present two cases of MS that under went complete surgical resection.

Keywords : Schwannoma; Melanotic schwannoma; Mediastinal tumors.

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