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Archivos argentinos de pediatría
Print version ISSN 0325-0075On-line version ISSN 1668-3501
Abstract
MICHELETTI, Eugenia et al. Antiphospholipid syndrome in Pediatrics: a case report. Arch. argent. pediatr. [online]. 2017, vol.115, n.6, pp.e412-e415. ISSN 0325-0075. http://dx.doi.org/10.5546/aap.2017.e412.
The antiphospholipid syndrome is a multisystem autoimmune disease in which autoantibodies against a variety of phospholipids and phospholipid binding proteins are produced. It occurs in 1.8% of the population and only 2% of the cases are pediatric. The spectrum of clinical manifestations is wide from asymptomatic patients to a life-threatening disease like the catastrophic antiphospholipid syndrome. Any organ can be affected. The most frequent manifestations in pediatrics correspond to venous thrombosis in 60% of patients, arterial thrombosis in 32%, hematological disease in 38% (thrombocytopenia, leucopenia), skin alterations in 18% (livedo reticularis, Raynaud's phenomenon) and neurological signs in 16%. We describe the case of a previously healthy 14-year-old female patient diagnosed with antiphospholipid syndrome.
Keywords : Antiphospholipid syndrome; Pediatrics.