Abstract

MORELLO, Graciela del Carmen; HEREDIA, Martha Beatriz  and  CACERES, Margarita Inés. Immunological test evaluation for neurosyphilis diagnosis. Acta bioquím. clín. latinoam. [online]. 2009, vol.43, n.2, pp.209-212. ISSN 0325-2957.

The results of 106 cerebrospinal fluids have been evaluated with the aim of correlating the VDRL (Venereal Disease Research Laboratory) and USR (unheated serum reagin) tests for neurosyphilis diagnosis. From 106 cerebrospinal fluids processed with VDRL and USR, 7.54% was reactive by the two methods, 90.57% was nonreactive by both methods and 1.89% was discordant. Mac Nemars test determined that VDRL and USR classified in the same way (not significative p). Although the VDRL in cerebrospinal fluids is the standard serologic test for neurosyphilis, the USR could be used as well for its diagnosis, since it is not significatively different from the statistical point of view with the VDRL; it is less expensive, more practical and more easily available in the market.

Keywords : Neurosyphilis diagnosis; Non-treponemal test; Cerebrospinal fluid.

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