Abstract

RODRIGUEZ, Carlos Hernán et al. Bacteremias by Acinetobacter spp. and carbapenems resistance. Acta bioquím. clín. latinoam. [online]. 2010, vol.44, n.2, pp.243-248. ISSN 0325-2957.

The incidence, risk factors and susceptibility of Acinetobacter bacteremia in patients from Hospital de Clinicas, University of Buenos Aires, were retrospectively analysed. One hundred and one patients were evaluated between 2002 and 2008. An increasing resistance to carbapenem in bacteremia was observed, rising from 50% in 2002 to 70% in 2007-2008. Significative risk factors for the acquisition of imipenem resistance Acinetobacter bacteremia included: previous use of imipenem (p<0.05), intensive care units stay (p<0.05), and polimicrobial bloodstream (p<0.05). Minocycline, tigecycline and colistin were active in all strains whereas sulbactam, cefepime, amikacin, gentamicin and levofloxacin showed a better activity among imipenem-susceptible isolates.

Keywords : Acinetobacter; Carbapenems resistance; Critical care; Bloodstream; Risk factors.

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