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Acta bioquímica clínica latinoamericana
Print version ISSN 0325-2957
Abstract
RANDAZZOI, Viviana; LA SALA, Luciano Francisco and COSTAMAGNA, Sixto Raúl. Determinants of infestation during an outbreak of trichinellosis in southwest Buenos Aires province. Acta bioquím. clín. latinoam. [online]. 2013, vol.47, n.3. ISSN 0325-2957.
The association between infestation, laboratory parameters and clinical signs was investigated in human patients exposed to Trichinella spiralis during an outbreak of human trichinellosis in southwest Buenos Aires province, Argentina. The degree of agreement between immunoserological tests commonly used for diagnosis of human trichinellosis was determined. Among exposed individuals, the presence of clinical symptoms and high concentration of the creatine phosphoquinase enzyme 7 days post-exposure was significantly associated with infestation by day 30 post-exposure. Contrarily, Randazzo V et al. a high level of eosinophils (>7%) 7 days post-exposure was not associated with infestation by day 30 post-exposure. Test agreement was highest between ELISA and Western Blot both by days 7 and 30 post-exposure.
Keywords : Trichinellosis; Outbreak; Concordance; Laboratory tests; Clinical signs.