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Acta bioquímica clínica latinoamericana
Print version ISSN 0325-2957On-line version ISSN 1851-6114
Abstract
BRICENO DIAZ, Berinna; LARES AMAIZ, Mary; CARIAS PICON, Diamela and ACOSTA GARCIA, Edgar. Serum adiponectin in obese, overweight, and normal weight adults and its relationship with cardiovascular risk. Acta bioquím. clín. latinoam. [online]. 2018, vol.52, n.1, pp.5-13. ISSN 0325-2957.
Adiponectin has been linked to insulin resistance, dyslipidemia and coronary disease. The purpose of the study was to evaluate the relationship between serum adiponectin levels and cardiovascular risk factors (CRF) in obese, overweight, and normal weight adults. The study was descriptive, correlational and cross-sectional in 73 adults between 20 and 40 years of age. Lipid profile, indicators of insulin resistance and serum adiponectin were determined. Weight, height and waist circumference were measured and body mass index and blood pressure were determined. The variables studied were related. The results showed that serum adiponectin levels for the total sample were, on average, lower in obese subjects compared to normal weight (p<0.01). These differences were found both in males and females (p<0.01). Additionally, the values were higher in women compared to men (p<0.01). Adiponectin correlated significantly with insulin resistance and most of the CRFs studied (p<0.01), except for total cholesterol and LDL-c. These findings suggest the utility of serum adiponectin as a potential marker of cardiovascular risk in adults.
Keywords : Adiponectin; Cardiovascular risk factors; Insulin resistance; Adults; Overweight; Obesity.