Abstract

GONZALEZ PONTORIERO, Elizabeth Mariana  and  CASTRO OCAMPO, Gerardo. Comparación de dos sistemas de medición de glucosa en sangre en pacientes adultos internados en una unidad de cuidados intensivos. Acta bioquím. clín. latinoam. [online]. 2021, vol.55, n.4, pp.421-428. ISSN 0325-2957.

The analytical performance of glucose determination is crucial for the management of critical patients. The objective of this research was to establish whether the glucose values determined by a point of care (POC) system were comparable with the laboratory’s usual use system. Sixty samples from critically ill patients were analysed. The measurement of serum glucose and whole blood was performed on the Cobas c 501 modular analyser and, at the POC, Cobas b 221, respectively. The correlation and agreement between the different methods was studied and the results compared with the international quality requirements. The analysis of clinical accuracy was performed in ways to monitor errors (Surveillance Error Grid). The average blood glucose in the Cobas b 221 was 149.96 mg/dL, while the average blood glucose in the Cobas c 501 was 148.37 mg/dL. The correlation coefficient obtained was 0.95. The concordance analysis showed that 5% of the values exceeded the two standard deviations. Based on the specifications of the international requirements, the results obtained did not reach the optimum performance. The analysis using error monitoring forms determined that 90% of the measurements were in the classification of risk grade A, while the rest were in risk grade B. The Cobas b 221 analyser presents the appropriate clinical characteristics to be used to replace in case of emergency in relation to the Cobas c 501 measurement system.

Keywords : Blood glucose; Critical patient; Point of care; Arterial gases.

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