Abstract

SOLOAGA, Rolando et al. Estudio multicéntrico argentino sobre la utilidad del panel BCID2 del Sistema FilmArray^TM en la detección de bacteriemias. Acta bioquím. clín. latinoam. [online]. 2021, vol.55, n.4, pp.455-460. ISSN 0325-2957.

The BioFire® BCID2 panel (BioFire, Salt Lake City, UT) uses multiplex PCR analysis from positive blood cultures with results within one hour. The objective of this study was to determine the performance of the method from positive blood cultures of septic patients in 5 hospitals in Argentina. A total of 121 patients and 124 episodes were included. With regard to microbial identification, the global sensitivity and that corresponding to the microorganisms included in the database was 94% and 97%, respectively. The sensitivity of BCID2 to detect CTX-M, KPC, NDM, VIM, IMP, mecA/C, vanA/B was 100% and the specificity was 99% for NDM and VIM and 100% for the rest. This led to changes in antimicrobial treatment in 57/98 episodes (58%). The BCID2 panel is an important tool for the adequacy of antimicrobial treatment of patients with sepsis.

Keywords : Multiplex PCR; FilmArray™; BCID2; Bacteremia.