Abstract

MOTTA, Estela et al. Características clínicas, epidemiológicas y de laboratorio en hepatitis autoinmune. Acta bioquím. clín. latinoam. [online]. 2024, vol.58, n.1, pp.5-5. ISSN 0325-2957.

Autoimmune hepatitis (AIH) is a progressive hepatocellular inflammation. Approximately 550 patients are treated per year in the Hepatology and Alcoholism Unit of the hospital, many of them with a diagnosis of AIH. The objective was to evaluate clinical and epidemiological characteristics and laboratory parameters of patients with AIH from 2012 to 2018; 44 patients were included, 40 with type I AIH and four seronegative patients. Ninety- one per cent were women aged between 13 and 68 years old. The most frequent form of presentation (54.5%) was acute hepatitis. Thirty-two patients required biopsy; 50% showed features of AIH (interphase hepatitis) and 35% had histologic cirrhosis. The study offers an approximate image of the particularities of AIH in the population treated in this hospital. Compared to other populations, this communication shows a higher percentage of female patients, with a high preponderance of acute presentation and associated autoimmune diseases.

Keywords : Autoimmune hepatitis; Clinical presentation; Epidemiology; Autoantibodies.

        · abstract in Spanish | Portuguese     · text in Spanish     · Spanish ( pdf )