Abstract

FOX, Barbara et al. Rapid syndromic molecular testing and human parechovirus infection in children: A report of three cases in Argentina. Rev. argent. microbiol. [online]. 2022, vol.54, n.1, pp.11-20. ISSN 0325-7541.  http://dx.doi.org/10.1016/j.ram.2021.02.003.

Human parechovirus (HPeV) is one of the members of the family Picornaviridae that has been associated with fever of unknown origin, gastroenteritis, clinical sepsis, meningitis, orencephalitis in very young infants. HPeV detection is not routinely performed in most clinical microbiology laboratories in Argentina and, therefore, its real prevalence is unknown. We here report three cases of HPeV CNS infection that presented to our hospital with different clinical features after the implementation of a multiplex PCR meningitis/encephalitis panel. Molecular diagnostic techniques could help improve patient care and understand the real prevalence of this infection in Argentina.

Keywords : Human parechovirus; HPeV-3; Neonates; CNS infection; Molecular diagnosis.

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