Abstract

CRUZ, Ana Rosa Méndez et al. Bloodstream infection by Rhodococcus corynebacterioides in a pediatric patient diagnosed with high-risk retinoblastoma. Rev. argent. microbiol. [online]. 2023, vol.55, n.1, pp.81-90.  Epub Mar 01, 2023. ISSN 0325-7541.  http://dx.doi.org/10.1016/j.ram.2022.06.001.

Rhodococcus is a pathogen that is known to cause infections in animals and humans, mainly in cases of immunocompromised patients. A case of a pediatric cancer patient suffering from a bloodstream infection caused by Rhodococcus corynebacterioides was described in this work. Gram positive rods were isolated from blood cultures. The target bacterium was identified using a combination of biochemical tests, the MALDI-TOF mass spectrometry technique, and the analysis of the 16S rRNA sequence. Moreover, an antimicrobial susceptibility test was performed using the E-test. The isolated bacterium was identified as R. corynebacterioides. The 3-year-old patient was successfully treated with vancomycin and meropenem. This is the first published report of R. corynebacterioides in a pediatric patient diagnosed with retinoblastoma that developed a bloodstream infection. R. corynebacterioides should be considered among the opportunistic infectious agents affecting pediatric cancer patients.

Keywords : Rhodococcus corynebacterioides; Bloodstream infection; Retinoblastoma; Identification methods; Actinomycete; Bacteremia; Cancer; Rhodococcus corynebacterioides; Infección del torrente sanguíneo; Retinoblastoma; Métodos de identificación; Actinomiceto; Bacteriemia; Cáncer.

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