Abstract

GAMBARO, Rocío Celeste; SEOANE, Analía  and  PADULA, Gisel. Comparison of supplementation strategies for the prevention and treatment of iron deficiency anemia. Rev Arg Antrop Biol [online]. 2023, vol.25, n.2, e065.  Epub June 01, 2023. ISSN 1514-7991.  http://dx.doi.org/10.24215/18536387e065.

The nutrition in the first 1000 days of human life is crucial to maintain the proper growth and development. In children one of the main malnutrition problems is iron deficiency. The Argentine Society of Pediatrics recommends daily doses with ferrous sulfate for preventive supplementation and also for therapeutic treatment, but in higher doses. Due to the adverse effects and the poor treatment compliance, the frequency of anemia iron deficiency continues to be very high which is why weekly supplementation emerges as an alternative. One of the invisible consequences associated with daily administration is that it can break the cellular balance and cause oxidative stress, causing damage to the main cellular biomolecules. The objective of this paper was to review the effectiveness of various forms of administration of preventive supplementation and therapeutic treatment for iron deficiency anemia. Likewise, studies where the effects of iron on oxidative stress and/or damage to biomolecules are evaluated. An exhaustive bibliographic search was carried out through different databases available online (Pubmed, Google Scholar, etc). Approximately 30 scientific articles in English and/or Spanish, carried out in vitro and in vivo, were selected. It is extremely important to review the current supplementation and treatment schemes to favor the design of adequate public health policies to deal with this universally distributed pathology. Rev Arg Antrop Biol 25 (2), 2023. https://doi.org/10.24215/18536387e065

Keywords : Preventive health services; therapeutics; iron; iron deficiency anemia.

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