Abstract

VILLASENOR,, Andrea Socorro Álvarez et al. Patients with COVID-19 and a history of vaccination. Salud(i)Ciencia [online]. 2022, vol.25, n.2, pp.75-81.  Epub Dec 20, 2022. ISSN 1667-8682.  http://dx.doi.org/10.21840/siic/170746.

Introduction: Vaccines against COVID-19 are effective. However, a percentage of people with a complete vaccination scheme are at risk of contracting and becoming ill from COVID-19. These cases are known as "vaccinated cases of infection". Objective: To identify the clinical characteristics of patients with SARS-CoV-2 infection with a history of vaccination for COVID-19. Methods: Retrospective cohort study in 271 vaccinated and positive patients who attended medical units in Baja California Sur, with or without a complete scheme and registered in SINOLAVE. Clinical characteristics, management, sequelae and mortality were analyzed. Descriptive statistics and association measures were used. Authorized by the ethics and research committees. Results: Age 48.5 ± 12.1 years, 19.5% met the definition of infection in vaccinated, 93% with outpatient management, 3.7% mortality, the most frequent comorbidity: diabetes/hypertension. 92% of the cases vaccinated with CanSino® had COVID-19, followed by Pfizer® with 26%. There is a higher risk of hospitalization and mortality in patients with an incomplete scheme. Conclusions: The vaccines are effective, most of the cases were ambulatory. Patients vaccinated with CanSino® showed a higher COVID-19 infection, the reinforcement of this vaccine could reduce the disease in patients already vaccinated. Of the patients who died, the majority did not have a complete vaccination schedule.

Keywords : COVID-19; SARS-CoV-2; COVID-19 vaccines; prevention; immunity.

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