Abstract

WOLFZUN, Camila; KORMAN, Guido Pablo  and  SARUDIANSKY, Mercedes. Quality of life in patients with epilepsy and psychogenic nonepileptic seizures: a systematic review. Interdisciplinaria [online]. 2022, vol.39, n.2, pp.89-104.  Epub Feb 14, 2022. ISSN 1668-7027.  http://dx.doi.org/10.1688/interd.2022.39.2.6.

Psychogenic non epileptic seizures (PNES) are disruptive changes in behaviour, thought, or emotion that resemble an epileptic seizure, but without paroxysmal neuronal discharge detectable by electroencephalography (EEG), and are not caused by another medical condition. On the other hand, epileptic seizures (ES) are defined as clinical events that reflect the presence of hypersynchronous discharges of neurons located in the cerebral cortex, which have the particularity of starting and ending abruptly. The diagnosis of epilepsy is made when an epileptic seizure was experienced and there is a risk of having another.

The objective of this paper is to present the results of a systematic review of articles that have studied quality of life in people with PNES and ES. This review has been performed following the PRISMA guide (Preferred Reporting Items for Systematic reviews and Meta-Analyses). Prior to the beginning of the search, a protocol was carried out and it is published for consultation in the International prospective register of systematic reviews (PROSPERO).

The review includes randomized and non-randomized, quantitative or mixed, cross-sectional or longitudinal studies, published in English or Spanish until 2020. In addition, participants had to be over 16 years old. PNES diagnosis must have been confirmed by video-electroencephalography (VEEG) or a similar procedure-which is considered the gold standard for the diagnosis of PNES.

Keywords : epilepsy; psychogenic non epileptic seizures; dissociative seizure; quality of life; health related quality of life.

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