Abstract

BENITEZ, J.S. et al. Valoración de características nucleares en muestras citológicas de tumores mamarios caninos. Rev. vet. [online]. 2016, vol.27, n.2, pp.117-120. ISSN 1669-6840.

This work aimed to validate the usefulness of subjective and objective determination of nuclear morphological characteristics in cytological samples of canine mammary tumors and check their predictive utility. Samples of 34 patients who were followed up for 18 months post surgery, were studied, situation that allowed survival curves confection.Clinical staging at diagnosis was made. The samples were obtained by fine needle punction, colored with hematoxylin and eosin and cytologic diagnosis and nuclear graduation were performed. The Leica Application Suite 3.4.1 Program was used for measurements, calculating the average nuclear diameter, the average nuclear area, the average nuclear perimeter and roundness index. All of these nuclear morphometric parameters are considered of prognostic value in human medicine. In this analysis, a gradual increase in morphometric values of each parameter was observed. In accordance with higher nuclear graduation and clinical stages and also, in histological types considered of worse prognosis. Survival curves showed statistical differences when comparing nuclear degrees. The findings obtained here, support the predictive quality of determination of nuclear grade and its morphometric parameters.

Keywords : bitch; mammary neoplasias; cytologic diagnosis; nuclear graduation; cariometric parameters; prognosis value.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )