Abstract

CARAMELLO, C.S.; JORGE, M.J.; JORGE, N.L.  and  JORGE, L.C.. Evaluation of herbicide glyphosate effects in the fish Prochilodus lineatus using chromosome aberration test. Rev. vet. [online]. 2017, vol.28, n.1, pp.65-68. ISSN 1669-6840.

The widespread use of glyphosate has been subject of numerous controversies since the prolonged exposure to low concentrations of this substance could lead to toxic effects. Then, the appearance of pathologies in medium and long term progressively will increase because of the exposure of people and animals through the consumption of contaminated water or food. Considering this, the aim of this study was to evaluate the potential mutagenicity of glyphosate herbicide in fish (Prochilodus lineatus) using the test of chromosome aberrations. The fish were exposed to 0,1 ug/l of glyphosate for 70 days. After this period, samples of the anterior portion of the kidney were extracted for chromosomal aberrations (CAs) analysis. A greater number of CAs (gaps, breaks, stickiness, endomitosis, fragmentations, and pulverizations) were observed in individuals exposed to the pesticide. The statistical analysis of the data showed significant differences between the control and treated groups. In this way, the results suggested the existence of a genetic response as a consequence of pesticide exposure in fish

Keywords : fish; glyphosate exposure; chromosome aberrations; mutagenesis.

        · abstract in Spanish     · text in English     · English ( pdf )