Abstract

BELZITI, CÉSAR A.. The Kidney in Heart Transplantation, Tale of a Journey. Rev. argent. cardiol. [online]. 2022, vol.90, n.2, pp.146-151.  Epub Apr 01, 2022. ISSN 1850-3748.  http://dx.doi.org/10.7775/rac.es.v90.i2.20499.

The aim of this update is to highlight the relationship between the heart and the kidney throughout the entire journey involved in heart transplantation.

Faced with heart transplantation, the cardiovascular and renal systems behave as mates of a journey that, at times, is difficult to determine when it starts, and that forces them to overcome different obstacles, such as hemodynamic changes, neurohumoral and inflammatory response, surgical injury, immune reaction, and drug toxicity. This relationship can be seen as an adventure that they must inevitably share.

We will try to accompany both organs in this journey, but paying special attention to the kidney, describing the associations and the protection and damage mechanisms that are generated throughout its course.

In this journey we can recognize solidarity responses to maintain the balance between both systems, but in this attempt to protect, collateral injury occurs.

Keywords : Heart transplant; Heart-kidney crosstalk; Acute kidney injury; Cardiorenal syndrome; Inflammation.