Abstract

MORENO, Alejandro; RODRIGUEZ GRANILLO, Alfredo Matías  and  PEREZ DE LA HOZ, Ricardo. Inflammation in acute myocardial infarction, impact on ventricular remodeling, and new therapeutic targets. Rev. argent. cardiol. [online]. 2023, vol.91, n.5, pp.359-364. ISSN 1850-3748.  http://dx.doi.org/10.7775/rac.es.v91.i4.20669.

Ischemic heart disease is the most common cause of heart failure, with a high incidence of heart failure despite early revascularization and neurohormonal modulation.In the acute myocardial infarction setting, necrotized cardiomyocytes induce activation of the innate immune system, increasing the levels of inflammatory cells to help remove dead cells and initiate a corrective response, which allows for proper scar tissue formation.A prolonged or expanded inflammatory response after infarction contributes to adverse ventricular remodeling and development of heart failure.Understanding the inflammatory mechanisms that emerge as a result of myocardial infarction and their impact on adverse remodeling that leads to an increased.

Keywords : Acute Myocardial Infarction; Inflammation; Ventricular Remodeling.

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