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Revista argentina de cardiología
On-line version ISSN 1850-3748
Abstract
CALVELO, Santiago A. Ahuad et al. Predictive Capacity of Different Surgical Risk Scores in Infective Endocarditis. Rev. argent. cardiol. [online]. 2023, vol.91, n.6, pp.428-434. Epub Nov 30, 2023. ISSN 1850-3748. http://dx.doi.org/10.7775/rac.es.v91.i6.20711.
Background.
Infective endocarditis (IE) is a life-threatening disease that may require surgical treatment. Despite being fundamental in decision making, surgical scores were not generated specifically to stratify the risk of this disease.
Objectives.
The objective of this study was to: To evaluate the predictive capacity of surgical risk scores adjusted for IE.
Methods.
Single-center observational and retrospective study of 270 patients > 18 years, hospitalized for active IE from 06/2008 to 02/2023, of which 70 (26 %) underwent central cardiac surgery. Device-associated endocarditis and patients who did not undergo cardiac surgery were excluded. The surgical risk scores analyzed were: EuroSCORE II, EURO-IE, STS-IE and PALSUSE (Prosthesis, Age >70, large cardiac destruction, Staphylococcus, Urgency, Female gender, EuroScore >10). The predictive capacity of each score was evaluated using the C statistic, calculating the area under the curve of the sensitivity/1- specificity relationship with their respective 95 % confidence intervals (CI), and statistical significance.
Results.
The median age (interquartile range, IQR) was 60 years (48-67) and the number of days of hospitalization were 23 (17-39). Forty-one patients (58.57 %) had a prosthetic valve. Regarding the causative germs, Staphylococcus was responsible for 30 % of the infections. The main indications for surgical treatment were heart failure (44%), abscess (19 %) and prosthetic dysfunction (12%). Annular abscess was observed in 28.57 % of patients. Urgent surgery was performed in 45.71 % and emergency surgery was performed in 7.14 %. Hospital mortality was 21.42 %. The predictive capacity of all scores was statistically significant, except for the STS-IE. The STS-IE score presented an area under the curve (AUC) of 0.586 (95 % CI 0.429-0.743). The EuroSCORE II, an AUC of 0.685 (95 % CI 0.541-0.830); the EURO-IE presented an AUC of 0.695 (95 % CI 0.556-0.834) and the PALSUSE an AUC of 0.819 (95 % CI 0.697-0.941).
Conclusion.
The results of this study suggest that the PALSUSE score was a better predictor of surgical risk in patients with active IE, compared to the Euroscore II, EURO-IE and STS-IE scores.
Keywords : Infective Endocarditis; Heart Valve Surgery; Mortality; Risk Score.