Abstract

RASTELLINI, SL. Merkel cell carcinoma: A case with atypical location and size. Rev. argent. dermatol. [online]. 2015, vol.96, n.3, pp.3-13. ISSN 1851-300X.

The Merkel Cell Carcinoma (MCC) is a rare malignant skin tumor, fast-growing, locally aggressive, prone to lymph node and distant metastases and high rate of local recurrence. Its pathogenesis is unknown, but has recently shown a virus replication inside (Merkel cell polyomavirus) which has led to a new field of research. It requires early diagnosis and surgical treatment and radiotherapy to improve the survival of patients. CCM case is reported in a 72 years at diagnosis by the histopathologic and immunohistochemical characteristics are confirmed, due  to the  atypical  presentation of large, fast-growing  and unusual location. A review of the peculiar disease and also the clinical course and treatment instituted, without recurrence at seven months of follow-up are described.

Keywords : Merkel cell carcinoma; Diagnosis; Immunohistochemistry; Therapeutics.