Abstract

CANDELO, P A; ARIAS, D A  and  VICTORIA, J. GENERALIZED MUCOCUTANEOUS CANDIDIASIS IN A CHILD WITH TYPE 1 POLYGENELLULAR SYNDROME: A CASE PROPOSED. Rev. argent. dermatol. [online]. 2019, vol.100, n.3, pp.101-105.  Epub Sep 30, 2019. ISSN 1851-300X.

Chronic Mucocutaneous Candidiasis is a non invasive persistent disease that has characteristics that include infection by Candida in skin, nails and mucous membranes, associated with several autoimmune diseases to genetic alterations in the immune system.

The mutation of the AIRE autoimmune regulatory gene is the main cause of chronic mucocutaneous candidiasis, although other genes have been totally or partially implicated with related clinical phenotypes. We have the case of a 15-year-old girl who entered to our clinic with immunosuppression, endocrinological alterations and Candida Albicans infection, which represented a diagnostic challenge.

Keywords : Candida Albicans; AIRE; Polyglandular syndrome.