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Revista argentina de dermatología
On-line version ISSN 1851-300X
Abstract
MONTI, F C; GARAY, I; KURPIS, M and LASCANO, A Ruiz. Clinical and histopathological characteristics of autoimmune blister diseases: a retrospective study in Private University Hospital of Córdoba. Rev. argent. dermatol. [online]. 2020, vol.101, n.4, pp.1-10. ISSN 1851-300X.
The autoimmune bullous diseases (ASD) comprise a heterogeneous group of pathologies with a low frequency of presentation that presents a chronic evolution, with remissions, exacerbations and an important morbidity and mortality even with early and adequate treatment. There are few epidemiological studies in our population that include the entire spectrum of bullous diseases.
Objectives
: To determine the clinical-epidemiological characteristics of AAS, describe treatments performed, control time of disease activity and time from treatment initiation to complete remission. Determine relapses of the studied pathologies, evaluating if there is a relationship between them and some recognized factor.
Materials and methods
: Retrospective and descriptive study. All patients with clinical, histopathological and immunofluorescence diagnosis of the AAS who had followed up for at least one year in the dermatology service of the HPUC, from January 2008 to November 2018 were included.
Results: 53 were included. patients of which 50.9% had Bullous Pemphigoid (BP), 22.6% Dermatitis herpetiformis (DH) and 17% Pemphigus Vulgaris (PV). The age of the patients was between 21 and 90 years. Tense blistering forms and erosions were the most common forms of presentation. Systemic treatments were performed in 74% of the cases. We recorded relapses in 63% of the cases and two cases of death during the treatment. More frequency of cardiovascular disease was established in patients with BP.
Conclusions
: It is the first retrospective work on EAA in our environment. Our findings allow determining an important frequency of PA in the dermatological consultation and DH, fact this last, not reported in other studies with similar populations.
Keywords : Autoimmune bullous diseases; Pemphigus; Pemphigoid; Dermatitis herpetiformis.
