Abstract

VILLA-BLASCO, M.C. et al. Graves-Basedow disease and thymic hyperplasia: an association that must not surprise us. Rev. argent. endocrinol. metab. [online]. 2018, vol.55, n.2, pp.51-55. ISSN 1851-3034.

Thymic enlargement associated with thymic hyperplasia (TH), in patients with Graves-Basedow disease (GBD) is common, although it remains largely unrecognized in routine clinical practice. We present the case of a 38 year-old woman with GBD, to whom an incidental thymic enlargement was detected. The patient did not have local compressive symptoms and the computerized tomography showed homogenous thickening of the anterior mediastinum suggestive of TH. During evolution, a reduction in size was observed after thyroid function was controlled by anti-thyroid drugs. The presence of some radiological features such as diffuse and homogeneous gland enlargement, absence of invasion of neighboring structures, calcifications or cystic images suggests the presence of TH. In these cases treatment of hyperthyroidism and expectant management are reasonable responses. Recognizing this evolution can avoid unnecessary diagnostic or therapeutic interventions.

Keywords : Graves-Basedow disease; Graves disease; Thymic hiperplasia.

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