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Revista argentina de endocrinología y metabolismo

On-line version ISSN 1851-3034

Abstract

E., Guillermo et al. Thyroidectomy in acute demyelinating polyneuropathy for a patient with Graves’ disease: a case report. Rev. argent. endocrinol. metab. [online]. 2018, vol.55, n.3, pp.71-80. ISSN 1851-3034.

There are few studies that describe the neuromuscular complications of hyperthyroidism. We present the case of a 36-year-old woman with a history of Graves’ disease in medical management, who presented motor and sensitive involvement in the lower limbs until compromising gait. Electromyography was compatible with acute demyelinating polyneuropathy, nuclear magnetic resonance suggested Guillain-Barré syndrome. Management with plasmapheresis was indicated, and thyroid therapy was adjusted with transient improvement. Subsequently, she presented neurological deterioration with ascending weakness and swallowing compromise; despite an immunoglobulin cycle regimen, clinical worsening persisted with the requirement of ventilatory support; thyroidectomy was performed resulting in clinical improvement and resolution of the condition.

Keywords : Guillain-Barre syndrome; Graves’ disease.

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