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Revista argentina de endocrinología y metabolismo

On-line version ISSN 1851-3034

Abstract

BELEN, L. et al. Glycaemic profile and its association with related factors insulin resistance in adult women without diabetes. Rev. argent. endocrinol. metab. [online]. 2018, vol.55, n.4, pp.31-40. ISSN 1851-3034.

Introduction:

The identification and intervention of the metabolic states prior to the diabetes mellitus type 2 (DM2), allows to avoid the appearance of the disease in a high percentage of the cases.

Objective:

To determine the risk factors associated with the values of fasting altered glycemia (GAA) in non-diabetic adult women, concurrent to nutritional consultation at the Endocrinological Center of the Autonomous City of Buenos Aires (CABA), Argentina.

Materials and methods:

Cross-sectional and analytical study in a non-probabilistic sample of 316 women (40 to 65 years) without diabetes and not pregnant, who were classified according to fasting glycemia in two Groups (Gl <100 mg/dl and Gl≥100 and <126 mg/dl). They were studied as risk factors related to GAA: increased waist circumference (WC) >88 cm, unhealthy body mass index (BMI) ≥27 kg/m2, physical inactivity (less than 150 minutes a week), arterial hypertension (HT: ≥140/90 mmHg) and elevated TG/HDL-C ratio (≥3). The statistical program SPSS 19.0 was used to calculate mean, standard deviation and Chi square test. The level of statistical significance was set at p <0.05.

Results:

The mean age was 53.6 (SD = 6.5) years (35.8% premenopausal and 64.2% postmenopausal). 33.2% of the sample had GAA. 52.8% had unhealthy weight and 45.3% had increased BCA. 66.5% were sedentary, 21.5% had a diagnosis of hypertension and 22.2% had a high TG/HDL-C ratio. GAA was significantly associated with HTA (p<0,001) and elevated TG / HDL-C ratio (p <0,001).

Conclusions:

The HTA values and the elevated TG/HDL-C ratio were the two factors that in this study were associated with GAA in this sample. Their research is recommended as early markers to prevent the risk of DM2.

Keywords : Altered fasting blood glucose; Prediabetes; Adult women.

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