Abstract

VALLEJOS, Augusto J. et al. Frecuency of carbapenemase-producing enterobacteriaceae in anal swabs from an adult unit intensive care. Rev. cienc. tecnol. [online]. 2022, n.37, pp.91-100. ISSN 1851-7587.  http://dx.doi.org/10.36995/j.recyt.2022.37.010.

Thecarbapenemase-producingenterobacteriaceae (CPE) are one of the main concerns of global health, mainly those that are encoded by plasmids. Theaimwasto describe theprogressofcolonizationby CPE in anal swabsofpatientsofintensivecareunit (ICU) and COVID-ICU in anadult hospital from Chaco province, Argentina. A descriptive retrospective study wascarriedoutbetween 2021 January to August. 379 anal swabswerestudied, in 26% (n=98) CPE weredetected. K. pneumoniae was the more frequent isolate. In January, in COVID-ICU, 18% of anal swabswhere positive, beingallidentified as KPC carbapenemase. In August, in COVID-ICU, the total ofpositive anal swabraisedto 81% and alldetectedcarbapenemasewere MBL type. In ICU, thepercentageof positive anal swabsincreasedfrom 14% in Januaryto 49% in August, whereboth KPC and MBL carbapenemasesweredetected. Of The total of colonized patients, 15% developed CPE infection. Active surveillance and control measures are necessary to keep down the spread of CPE.

Keywords : Anal swabs; Carriagestudies; Carbapenemases; Active surveillance; Metalobetalactamases.