Abstract

DE VEDIA, Lautaro et al. Community acquired methicillin-resistant Staphylococcus: A new threat. Rev. amer. med. respiratoria [online]. 2012, vol.12, n.4, pp.131-139. ISSN 1852-236X.

Objectives: To know the incidence of Community Acquired Pneumonia (CAP) caused by Methicillin Resistant Sthaphylococcus aureus (MRSA), to examine their clinical and developmental characteristics and to analyze risk factors. Materials and Methods: Retrospective, descriptive and observational study carried out at a Respiratory Intensive Care Unit, between 2006 and 2012. Results: 180 patients with etiologic diagnosis of CAP were evaluated. The most common causes were Streptococcus pneumoniae (50.5%), Haemophillus influenzae (18.3%) and MRSA (12.2%, 22 cases). Community Acquired MRSA (CA-MRSA) pneumonia was present in young people, especially in male. In 81.8% of the cases, skin and related structure infections (SRSI) were the primary focus, 95.4% presented clinical criteria of sepsis, 72.7% had bilateral radiology involvement and 45.5% developed pleural effusion. 40.9% needed mechanical ventilation and 45.4% used vasoactive drugs. Clinical stability at the first week was not reached in 81.8% and mortality rate was 36.6%, significantly higher than for pneumonia caused by other microorganisms (8.8% p< 0,001). Clinical factors related with high risk of CA-MRSA pneumonia were the concomitant presence of SRSI, bilateral radiology involvement, clinical criteria of sepsis, age < 30 years old and need for vasoactive drugs. Factors related to CAP mortality were CA-MRSA aetiology and bilateral radiology involvement. Conclusions: CA-MRSA pneumonia is an emergent disease with high morbidity and mortality. It must be considered in young patients, with SRSI, bilateral radiology involvement, clinical criteria of sepsis or intake of vasoactive drugs.

Keywords : Pneumonia; CAP; CA-MRSA.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )