Abstract

RIZZO, Guillermina et al. Antisynthetase Syndrome in Patient with COP as Pulmonary Disease. Rev. am. med. respir. [online]. 2020, vol.20, n.3, pp.282-284. ISSN 1852-236X.

The antisynthetase syndrome is an autoimmune inflammatory miopathy that may show interstitial pulmonary involvement. The presence of antisynthetase antibodies is related to a higher incidence of interstitial pulmonary involvement. The imaging and anatomopathological pattern of diffuse interstitial pulmonary disease (DIPD) is variable, mainly inflammatory. This case describes a female patient with inflammatory miopathy and pulmonary involvement who shows a tomographic pattern of organizing pneumonia. It is important to increase suspicion for antisynthetase syndrome in a patient with pulmonary involvement and miopathy, where multidisciplinary evaluation is fundamental to reach a diagnosis. A review of the evidence is made in the discussion of the case.

Keywords : Antisynthetase syndrome; Antisynthetase antibodies; Organizing pneumonia.