Abstract

RODRIGUEZ-FRANCO, José H et al. Comportamiento epidemiológico del osteosarcoma en la población mexicana entre 2005 y 2014. Rev. Asoc. Argent. Ortop. Traumatol. [online]. 2016, vol.81, n.3, pp.219-226. ISSN 1852-7434.

Introduction: Osteosarcoma represents 15% of bone neoplasms. In Mexico, it accounts for 4.5% of neoplasms and 46.6% to 74% of malignant bone tumors with a slight predominance of teenage males, 50-80% affects the knee and proximal humerus. Objective: To identify the distribution, relative frequency and tendency of osteosarcoma and its projection to five years. Methods: Epidemiologic study of a patient database with histological diagnosis of osteosarcoma from 2005 to 2014. Age, gender, diagnosis, location, side and stage were analyzed using descriptive statistics and dispersion. Results were measured with Pearson's index and lineal regression analysis by the least squares method. Results: We analyzed 4,744 cases. Osteosarcoma had a frequency of 3.29% and it accounted for 56.2% of primary malignant bone tumors. Patients´ age was 18.6 ± 16.8 years old with higher incidence in the second decade of life (54.1%); men to women ratio was 1.64:1. Osteosarcoma affected the knee in 55.8% of the cases, followed by the proximal humerus (7.1%). Predominant histologic subtype was osteoblastic (76.9%). IIB stage was more frequent (77.6%), followed by IIIB (13.8%). To five years, an increased incidence of osteosarcoma is predicted. Conclusions: This is the largest case series of osteosarcoma in Latin America. A rising incidence of osteosarcoma is predicted. It is necessary to identify risk factors to establish this particular behavior.

Keywords : Osteosarcoma; Epidemiology.

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