Abstract

TISCORNIA, María Paula; FROLA, Marisa; DIOMEDI, Mabel  and  MARANGONI, Alberto. Evaluation of diagnostic underestimation and incidence in BI-RADS 3, 4 and 5 nodules studied by ultrasound- guided core biopsy. Rev. argent. radiol. [online]. 2011, vol.75, n.4, pp.325-329. ISSN 1852-9992.

Objectives. To retrospectively determine the false negatives rate and the extent of underestimation of ultrasound-guided core biopsy of breast nodules, and to determine the incidence of the various lesions presenting as breast nodules. Materials and Methods. We studied core biopsies of breast nodules from January 2000 to September 2010, performed by a radiologist with 10 years experience in breast imaging, using 14-gauge and 10-cm needles. For ultrasound guidance, two ultrasound machines with a 5-12 MHz linear transducer were used. Biopsied lesions had a moderate or high suspicion of malignancy (BI-RADS 4 and 5) and some were probably benign lesions (BI-RADS 3). Histological findings of core-biopsy were correlated with those of surgery for each lesion. Cases of benign lesions which had not been operated on underwent a 1- to 10-year clinical and radiological follow-up. Results. A total of 190 biopsies were performed. The false negative rate was 3%, sensitivity was 95% and specificity was 100% (PPV 100% and NPV 95%). Discussion. There was 94% consistency between core biopsy results and surgery. The false negative rate is acceptable as compared to other reports, where it ranges from 0 to 8%. Conclusions. This study indicates that ultrasound-guided core biopsy is a valid method, with a high degree of accuracy and a low rate of false negatives and underestimation, in the diagnosis malignant and benign of breast nodules. This has been confirmed by surgical excision and / or clinical and imaging follow-up of different lesions.

Keywords : Breast; Breast nodule; Core-biopsy.

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