Abstract

CASTRILLON, G. A et al. Hepatospecific Agents, Current Uses: More than the Characterization of Focal Lesions. Rev. argent. radiol. [online]. 2018, vol.82, n.1, pp.13-27. ISSN 1852-9992.  http://dx.doi.org/10.1055/s-0038-1637027.

With gadoxetic acid the dynamic enhancement of the lesions is equal to the other extracellular contrast agents. Its main utility is in obtaining a hepatobiliary phase that allows to characterize the lesions that contain functional hepatocytes as it would be the case of the regenerative nodules and focal nodular hyperplasia. Lesions without functional hepatocytes or that are devoid of bile ducts appear hypointense with respect to the hepatic parenchyma at this stage, which occurs in adenoma, high-grade dysplastic nodules, hepatocarcinoma, and metastases among others. Making this differentiation, the management of the focal lesion would change, allowing us, in most cases, characterizing lesions containing functional hepatocytes as benign and therefore that dont require biopsy, of those that may require histological confirmation. Other uses of these contrast media are the evaluation of the integrity of the bile duct especially in post-surgical stages and the differentiation of cysts that have communication with the bile duct of those who are simple hepatic cysts. The objective of this article is to perform a review of the current evidence about the emergent role of organ specific agents, not only for the evaluation of liver focal lesions, but also other utilities such as analysis of biliary pathology.

Keywords : Liver; Contrast media; Magnetic resonance imaging.

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