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Revista de nefrologia, dialisis y trasplante
On-line version ISSN 2346-8548
Abstract
SANCHEZ-ORO, Raquel and ALONSO-MUNOZ, Elsa María. INMUNOGLOBULIN G4-RELATED KIDNEY DISEASE. Rev. nefrol. dial. traspl. [online]. 2020, vol.40, n.4, pp.341-348. ISSN 2346-8548.
Immunoglobulin G4-related disease (IgG4-RD) is an immunomediated fibroinflammatory process. In the last few decades, this disease has been recognized as a systemic disorder encompassing individual involvement of organs, previously unrelated and known as independent entities. Renal involvement in IgG4-RD may be both synchronous and metachronous to other organ compromise, such as that seen in autoimmune pancreatitis, sclerosing cholangitis, retroperitoneal fibrosis, or IgG4-related lymphadenopathy. In this review we present the most frequent manifestations of renal involvement due to IgG4-RD, highlighting the role of imaging tests. The treatment of both IgG4-RD in general and renal involvement in particular are glucocorticoids. It is important to know about this disease, be suspicious about it and make an early and accurate diagnosis.
Keywords : inmunoglobulin G4; IgG4; IgG4-related kidney disease.