Abstract

VALDEZ, Silvina N. et al. Guía práctica para la solicitud de marcadores humorales de autoinmunidad y estudios genéticos en diabetes mellitus. Rev. Soc. Argent. Diabetes [online]. 2022, vol.56, suppl.1, pp.15-18. ISSN 0325-5247.

Diabetes mellitus (DM) is a heterogeneous disease, with diverse clinical phenotypes, all with hyperglycemia. Historically, four factors have been used to identify this diversity: the age at onset, the severity of the disease, that is, the degree of loss of beta cell function and insulin resistance, and the presence of circulating autoantibodies.

Currently, the parameters used to classify the different types of DM make it difficult to diagnose and treat patients. The different clinical manifestations require an accurate diagnosis to achieve an effective therapeutic approach through the use of immunogenetics and clinical biochemistry.

This practical guide aims to accurately classify the often uncertain clinical presentations within the two main types of diabetes.

Keywords : genetic; autoantibodies; classification; clinical diagnosis.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )