Abstract

GORBAN DE LAPERTOSA, Silvia Beatriz; MINO, Claudia Alejandra; LLANOS, Isabel Cristina  and  GONZALEZ, Claudio Daniel. Asociación entre uricemia y síndrome metabólico en un centro hospitalario de Corrientes. Rev. Soc. Argent. Diabetes [online]. 2022, vol.56, n.3, pp.83-92. ISSN 0325-5247.

Introduction: in recent years, numerous scientific evidence suggest that hyperuricemia may play a role in the development of metabolic syndrome (MS). Some studies have explored the association between uricemia and the presence of MS. However, it remains unclear whether high uric acid levels are causally related to the development of MS. Moreover, there are few studies on the presence of metabolic syndrome and its relationship with uric acid (UA) levels in the city of Corrientes, Argentina.

Objectives: to determine the relationship between serum UA levels and the parameters that define MS in patients attending the outpatient clinic of Medical Clinic and General Medicine of the Ángela I. de Llano Hospital, Corrientes.

Results: a total of 435 patients over 18 years of age were included: 312 (72%) women and 123 (28) men. Fifty-eight percent of the population met the NCEP-ATP III criteria for MS (60% females and 52% males). Seventy-five percent of the population had hyperuricemia and MS. In this study the presence of MS was significantly associated with uricemia values OR:1.5 (95%CI:1.3-1.8). The association is statistically significant.

Conclusions: the results show that the increase in the frequency of the components of MS, goes in direct relation with the increase in serum UA levels and that the cut-off value for this association is 4 mg/dl. Hence the importance of considering the determination of serum UA levels as a possible predictor of MS.

Keywords : metabolic syndrome; uric acid; hyperuricemia.

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