Abstract

RABAGO, Carlos et al. Efficacy and cost-utility of first total hip and knee replacement in patients with osteoarthritis. Rev. argent. reumatolg. [online]. 2017, vol.28, n.4, pp.9-17. ISSN 0327-4411.

Objectives: To determine the efficacy, costs and incremental cost-utility ratio (ICER) of first hip and knee total replacement in patients with osteoarthritis. Material y methods: We designed an uncontrolled before-after trial, including patients with primary hip and knee osteoarthritis waiting for first total joint replacement. Patients were followed for 12 months. Data collection included functional capacity ENT#091;short version of Knee Injury and Osteoarthritis Outcome Score (KOOS-PS) and Hip Disability and Osteoarthritis Outcome (HOOS-PS)ENT#093;, and quality of life (EUROQOL-5D). Cost analysis were performed form societal perspective, determining efficacy, quality of life and life expectancy (QALY), and ICUR. A p-value of 0.05 was considered statistical significant. Results: We included 23 patients ENT#091;coxarthrosis (52%), gonarthrosis (48%)ENT#093;. Patients showed a statistical significant improvement in functionality and quality of life one year after surgery ENT#091;mean difference: EUROQOL=0.69, HOOS-PS=-49, KOOS-PS=-31ENT#093;. Patient gained an average of 0.43 QALYs. The cost of surgery, including 12 months follow-up, was 141,343 Argentinean pesos (ARS), being the surgery incremental cost of 3140 ARS per patient. The ICUR was 7302 ARS per QALY. Conclusion: The total joint replacement result to be a “highly cost-effective” procedure, improving functionality and quality of life in patients with knee and hip osteoarthritis.

Keywords : total joint replacement; efficacy; cost-utility; gonarthrosis; coxarthrosis; Argentine.

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