Abstract

ORTUNO LOBO, Rossio Gardenia et al. Antisynthetase syndrome: a case report. Rev. argent. reumatolg. [online]. 2022, vol.33, n.1, pp.35-38. ISSN 0327-4411.  http://dx.doi.org/10.47196/rar.v33i1.372.

Anti-synthetase syndrome is a rare autoimmune inflammatory myopathy characterized by autoantibodies against tRNA synthetases (most commonly anti-Jo1) with clinical features that include myositis, interstitial lung disease, polyarthritis, mechanic’s hands and Raynaud’s phenomenon. We report a 45-year-old woman who presented with dermatomyositis phenotypical features and a significant improvement with corticosteroids and metotrexate treatment.

Keywords : antisynthetase syndrome; anti-Jo1; autoimmune inflammatory myopathy; mechanic's hands; interstitial lung disease.

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