Abstract

DELL'ELCE, A; AGUIRRE, MS; PATRICELLI, P  and  FORMENTINI, E. Actividad bactericida in vitro de miel sobre Escherichia coli y Staphylococcus aureus: Comparación con la actividad de cefalosporinas. FAVE, Secc. Cienc. vet. [online]. 2018, vol.17, n.1, pp.12-17. ISSN 2362-5589.

A comparative study was conducted between the antibacterial activity of honey and cephalexin against a strain of Escherichia coli and honey and cefquinome against a strain of Staphylococcus aureus by modified time-kill-curves essays. In all trials, the maximum antibacterial activity of honey was observed at a dilution of 50% v/v. Regarding the comparative efficacy between honey and antibiotics, it was observed that against E. coli, cephalexin achieved a reduction in viable bacteria count compatible with a bactericidal effect (<500 cfu/mL), while honey did not overcome this breakpoint. The opposite was observed for S. aureus, where honey achieved a reduction in the viable bacteria count compatible with a bacterial eradication effect (<50 cfu/mL) with respect to the bactericidal effect obtained with cefquinome (<500 cfu/mL). These preliminary results corroborate the need to revalue the antibacterial activity of natural products, whose efficacy - although empirically - was already known since antiquity and was forgotten after the appearance of antibiotics.

Keywords : Honey; Antibacterial activity; Escherichia coli; Staphylococcus aureus.

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