Resumen

VILLASENOR,, Andrea Socorro Álvarez; MONTOYA,, Yessenia Kristel Díaz; REYES,, Luis Rodolfo Paredes  y  CASTRO,, Matías Saúl Mier. Segmental mesenteric ischemia as a sequel to COVID-19: A case report. Salud(i)Ciencia [online]. 2022, vol.25, n.3, pp.154-163.  Epub 20-Ene-2023. ISSN 1667-8682.  http://dx.doi.org/10.21840/siic/169410.

Coronaviruses can cause respiratory, gastrointestinal, and central nervous system diseases in humans and animals, have the ability to adapt through mutations, and are programmed to modify host tropism. SARS-CoV-2 infection (COVID-19) has been shown to be a highly thrombogenic disease, generating deep vein thrombosis, pulmonary embolism and acute ischemia, in patients even without previous pathology. Coronaviruses can cross the species barrier and infect humans with unexpected consequences for public health. The transmission rate of SARS-CoV-2 is higher compared to that of closely related SARS-CoV infections. Key residues of the spike protein have a higher binding affinity for ACE2. These may be the reason for the higher transmission rate of SARS-CoV-2. COVID-19 has been shown in some patients to be a highly thrombogenic disease, both venous and arterial, generating deep vein thrombosis, pulmonary embolism and acute ischemia, both in patients without previous pathology as with them.There is molecular evidence of the state of hyper coagulability in COVID-19; the first observations were made by Wang, in 2020, when analyzing the levels of fibrinogen and D-dimer in patients with COVID-19 and finding elevated levels up to 75% above the laboratory controls. We present the case of a 62-year-old male with mild symptoms of COVID-19 and outpatient management, at the end of the clinical disease he presented an acute abdomen secondary to mesenteric ischemia, with good postoperative evolution.

Palabras clave : COVID-19; bowel ischemia; thrombosis; acute abdomen; SARS-CoV-2.

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