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Revista argentina de dermatología
versión On-line ISSN 1851-300X
Resumen
OTAL, FJ Mira y VIVANCOS, F. NEW EVIDENCES IN STRESS ALOPECIA: ROLE OF NUTRICOSMETICS WITH PASSIFLORA. Rev. argent. dermatol. [online]. 2018, vol.99, n.4, pp.8-22. ISSN 1851-300X.
Stress is a trigger for telogen effluvium and other types of alopecia and makes it difficult to control. The "brain-hair follicle axis" establishes that stress alters the hair follicle cycle, prematurely ending its growth and activating apoptosis and various harmful inflammatory events around the follicle. Substance P, an immunomodulatory neuropeptide, plays a key role in this cascade. The extract of passionflower (Passifloraincarnata L.), authorized by the EMA for the temporary relief of mild symptoms of mental stress, has shown to be effective and safe against the stress underlying alopecia. It acts on substance P and on the neurotransmission system of gamma-aminobutyric acid (GABA), in addition to its antioxidant properties. The available evidence is reviewed below.
Palabras clave : loss,telogen effluvium,passiflora,stress,substance P..