Resumen

REYES MORELO, MT et al. Sole of feet lesions in pediatric patients: a purpose of two cases. Rev. argent. dermatol. [online]. 2021, vol.102, n.1, pp.11-20. ISSN 1851-300X.

Mastocytosis and histiocytosis are diseases that are characterice by uncontrolled proliferation or activation and subsequent abnormal activation of mast cells and histiocytes respectively.

Of unknown incidence, perhaps because they are underdiagnosed, their pathogenesis is still unknown although it is related to mutations in the C-KIT pathway for mastocytosis and of viral or neoplastic origin in the case of histiocytosis. Both pathologies are usually frequent in childhood, even some are congenital.

The single cutaneous mastocytoma would be a benign form of mastocytosis and the histiocytosis of Langerhans cells is a form of histiocytosis that in our case affecting a single organ (the skin) will have a good prognosis.

Palabras clave : Mast cells; Langerhans cells; proliferation.

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