Resumen

BERTINI, K et al. Osteoimmunology: An Integrated Vision of Immune and Bone Systems. Novel Perspectives for Bone Disease. Rev. argent. endocrinol. metab. [online]. 2014, vol.51, n.4, pp.197-204. ISSN 1851-3034.

The objective of this communication is to review the immune mechanisms involved in the pathogenesis of bone damage in some autoimmune diseases. As they are numerous (autoimmune polyendocrinopathy , celiac disease, Crohn's disease, ulcerative colitis, HIV, rheumatic diseases, bronchial asthma, pernicious anemia, periodontitis, etc.), we selected only four: Rheumatoid Arthritis, because of its typical bone lesions; post­menopause, because the immune components are not so often described; HIV, because of the current longer survival time with higher possibilities of bone lesions, and Periodontitis, in order to have an overview of dental aspects of this pathology. In many cases, knowledge of these mechanisms has contributed to the de­velopment of specific drugs that have led to therapeutic success and an improved quality of life. Rev Argent Endocrinol Metab 51:197-204, 2014 No finantial conflicts of interest exist.

Palabras clave : Autoimmune diseases; Bone damage.

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