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Revista americana de medicina respiratoria

versión On-line ISSN 1852-236X

Resumen

UBAL, Leonardo German et al. Influence of SARS-CoV-2 On the Progression of Infection to Tuberculous Disease. About 3 cases. Rev. am. med. respir. [online]. 2023, vol.23, n.1, pp.32-36. ISSN 1852-236X.  http://dx.doi.org/10.56538/ramr.kqwo9728.

Introduction:

SARS-CoV-2 is likely to favor the transition from infection to tuberculosis disease. Although information is limited, there is progress in understanding the inter action between COVID-19 and Tuberculosis. New investigations yielded unexpected similarities in the pathogenesis and evolution of the coinfection. Prolonged lymphopenia, hyperinflammation, lung tissue injury, and imbalance in CD4+ T-cell subsets associated with COVID-19 could propagate M. tuberculosis infection and disease progression.

Clinical cases:

we present three young patients, without comorbidities, with risk factors for Latent Tuberculous Infection, diagnosed with pulomonary Tuberculosis post mild COVID-19, treated symptomatically (not corticosteroids).

Discussion:

These cases raise the probable impact of SARS-CoV-2 in the transition from Latent Tuberculous Infection to disease, excluding the already proven influence of corticosteroids and severe forms of COVID-19. There is increasing evidence to sup port this idea.

Palabras clave : COVID-19; SARS-CoV-2; Tuberculosis.

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