Resumen

DENISE, Karpenko Wilman Ingrid et al. Nutritional assessment and muscle strength measured by dynamometry in patients with cystic fibrosis in an adult center. Diaeta [online]. 2021, vol.39, n.176, pp.24-31.  Epub 10-Mayo-2022. ISSN 1852-7337.

Introduction: in Cystic Fibrosis (CF) the pancreatic involvement, malabsorption, chronic inflammation, increased energy expenditure due to respiratory work, and the development of CF-Related Diabetes (CFRD) predispose to malnutrition, thus nutritional monitoring is essential.

Objectives: to assess the nutritional status of CF patients in an adult center at the first medical appointment in 2019. To evaluate the association between muscular strength (MS) and other nutritional parameters and pulmonary function.

Materials and method: cross-sectional, observational, in 30 patients. MS was evaluated with digital dynamometer. Triceps skinfold and arm muscle circumference were used to determine adipose mass and muscle mass. For pulmonary function: forced expiratory volume in 1 second (FEV1). Statistical analysis with SPSS 20.0 program: Chi-square and T-Student (p <0.05).

Results: median age of 22 years old (IQR= 19,75; 27,25), 36,7% women. 76,7% had exocrine pancreatic insufficiency (EPI), of which 39,1% CFRD. Of the total, 30% presented decreased MS.

Although 80% had body mass index (BMI) ≥18,5kg/m2, only 20% reached a desirable BMI. 50% presented decreased muscle mass and 46,7% decreased adipose mass.

A statistically significant association was found between MS and the following variables: muscle mass (p=0,001); low weight (p=0,001); CFRD (p=0,008) (OR:12, CI 95% 1,89; 76,15) and adipose mass (p=0,046) (OR:7, CI 95% 1,14; 42,96). Lower FEV1 (p=0.017) and lower BMI (p=0.002) were associated with MS. No statistically significant association was found between decreased MS and EPI.

Conclusion: decreased MS in CF patients is common and was associated with decreased muscle and adipose mass, low weight, CFRD, and pulmonary function. More studies are needed, so as to obtain comparable data on the nutritional status in specialized care centers. Nutritional assessment is an integral part of monitoring; carrying it out exhaustively and protocolized, including body composition analysis and MS is of great importance for decision making.

Palabras clave : cystic fibrosis; dynamometry; muscle strength; nutritional status.

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