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Revista argentina de radiología
versión On-line ISSN 1852-9992
Resumen
PEREZ-AKLY, Manuel S. et al. Correlation between visual scales of entorhinal and temporomesial atrophy with hippocampal volumetry. Rev. argent. radiol. [online]. 2023, vol.87, n.4, pp.149-154. ISSN 1852-9992. http://dx.doi.org/10.24875/rar.22000058.
Objective:
In patients with Alzheimers disease (AD), early neuropathological changes in the entorhinal cortex have been described, which precede temporomesial involvement. The evaluation of hippocampal atrophy using visual scales and volumetry are useful tools in the assessment of patients with cognitive impairment. Our objective is to establish the correlation between the visual evaluations of entorhinal cortex atrophy (ECA), temporomesial atrophy (TMA), and hippocampal volume.
Material and methods:
Retrospective cross-sectional study. Patients with cognitive complaint and brain magnetic resonance imaging (MRI) were included. ACE and TMA visual scales were used. Hippocampal volume was measured using the volBrain 1.0 software.
Results:
Forty-eight patients were included, 31 were women (64.6%). Median age was 76.5 (IQR: 69-83). The correlation between ECA and TMA on the right side was 0.67 (p < 0.0001) and on the left side was 0.69 (p < 0.0001). We found a negative moderate correlation between ECA and hippocampal volume, on the right side it was 0.59 (p < 0.0001) and on the left side it was 0.42 (p = 0.003).
Conclusion:
The ECA scale shows high correlation with the TMA scale and moderate correlation with hippocampal volume. Its use could provide valuable information for the assessment of cognitive disorders.
Palabras clave : Entorhinal cortex; Hippocampus; Alzheimer disease.