SciELO - Scientific Electronic Library Online

 
vol.40 número4POR QUÉ LOS DONANTES Y RECEPTORES POTENCIALES NO PROCEDEN AL TRASPLANTE DE RIÑÓN VIVO, ALGORITMO DE MALATYA índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

  • No hay articulos citadosCitado por SciELO

Links relacionados

  • No hay articulos similaresSimilares en SciELO

Compartir


Revista de nefrologia, dialisis y trasplante

versión On-line ISSN 2346-8548

Resumen

DEL VALLE, Elisa Elena et al. BONE-MINERAL METABOLISM IN 4,620 PREVALENT PATIENTS IN CHRONIC HEMODIALYSIS IN ARGENTINA. Rev. nefrol. dial. traspl. [online]. 2020, vol.40, n.4, pp.295-302. ISSN 2346-8548.

Introduction

: Abnormalities of bone mineral metabolism begin from the early stages of CKD, causing the development of bone disease and increased morbidity and mortality of patients. Objectives: To know, in a representative sample of our hemodialysis patients, the prevalence of patients in the target range of PTH values, secondary hyperparathyroidism and adynamic bone disease according to the KDIGO guidelines, also evaluating the use of different drugs in the control of these alterations. Methods: 39 hemodialysis centers from our country participated, who sent the latest determinations of calcium, phosphorus and PTH and the medication received in the management of mineral metabolism. Results: 4620 prevalent hemodialysis patients > 18 years were included, mean age 57 years, men 57.4%. The means were calcemia 8.6 and phosphatemia 4.9 mg/dl. 56.7% and 50.3% were in the calcemia and phosphatemia range, respectively. The average PTH was 601 and the median 437 pg/ml. 50.5% had PTH in range, 15% below 150 pg/ml and 34.5% above 600 pg/ml. In relation to medication, 47% of the patients received calcium chelators with extreme use ranging from 4.5-8% in some centers to 83-94%. 28.8% received Sevelamer, calcitriol 38%, paricalcitol 11% and cinacalcet 20%, its use being variable according to the centers from 3% to 52%. Conclusion: the presence of secondary hyperpartyroidism was more frequent than desired, probably linked to the difficulty in the adequate use of medications.

Palabras clave : hemodialysis; renal dialysis; bone-mineral metabolism; alterations; pharmacotherapy.

        · resumen en Español     · texto en Español