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Medicina (Buenos Aires)
versión impresa ISSN 0025-7680versión On-line ISSN 1669-9106
Resumen
GREGORI SABELLI, Rosana et al. Extracorporeal support treatment in severe malaria. Medicina (B. Aires) [online]. 2023, vol.83, n.5, pp.828-831. ISSN 0025-7680.
Malaria is a wide-spread disease in tropical areas. The severe form is characterized by organic involve ment and/or hyperparasitaemia. Criteria for early monitoring in intensive care rooms are defined; with out a timely and early treatment, severe malaria has a 100% mortality. Although the literature in these cases is not extensive, extracorporeal therapy used sequentially for hepatic and renal detoxification is a useful and safe tool that can be used in intensive care. We describe the case of a 36-year-old man with a diag nosis of severe malaria according to WHO criteria. He began treatment with intravenous artesunate and due to a torpid evolution, a sudden increase in bilirubine mia with encephalopathy, parameters of acute kidney injury and acute pulmonary edema, undergoes extra corporeal sequential treatment, coupled with plasma filtration adsorption, high-exchange plasmapheresis, and continuous hemodiafiltration with favorable evo lution. This case shows that extracorporeal support in trained hands and in a timely manner is effective when organ failure evolves rapidly to achieve stability and provide necessary time for definitive treatment, in this case rapid action antimalarials until parasitemia becomes negative.
Palabras clave : Serious malaria; Plasmapheresis; Extra corporeal therapies.